The primary challenge of developing an effective health information system is maintaining a satisfactory balance between health care information system safety and health care data and information availability. Healthcare data safety is defined, the need for establishing high availability architecture is examined, and a variety of the components of performing replication, recovery and backups for healthcare data are discussed. In addition, the components of Oracle Active Guard as technologies for guarantee high availability of data, quick loading and finding data in huge storages like health care information are outlined. Keywords: healthcare information system, business intelligence, high availability, backup, data protection, Oracle, Active Data Guard, GoldenGate.