Regimen adherence is a key factor in the success of home monitoring of lung transplant recipients. Patients generally adhere satisfactorily with home spirometry in the short-term, but adherence tends to decline over time. Telehealth and Internet technology provide new methods to address this issue. The unique contribution of the Adherence Enhancement Internet Program (AEIP) is the integration of multiple adherence enhancement strategies operating in a unified approach to the adherence problem, while meshing all user groups to facilitate interactions. This Internetbased program focused on promoting subject specific strategies was developed to maintain the initial high levels of adherence beyond the first year post transplant. The program provides more immediate subject feedback related to home monitoring data, reminders from the patient’s health care providers, educationalmaterial, and guidance in dealing with subject specific barriers to maintaining adherence. It also simplifies communication betwee